Primary Identifier | MGI:1891763 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 56420 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable lamin binding activity and protein serine/threonine phosphatase activity. Predicted to be involved in double-strand break repair via homologous recombination; negative regulation of protein phosphorylation; and regulation of double-strand break repair via homologous recombination. Located in cytoplasm and nucleus. Part of protein phosphatase 4 complex. Is expressed in several structures, including brain; neural retina; olfactory epithelium; skeletal muscle; and thymus primordium. Used to study oligoasthenoteratozoospermia. Orthologous to human PPP4C (protein phosphatase 4 catalytic subunit). PHENOTYPE: Embryonic Ppp4c-deficiency leads to early embryonic lethality. [provided by MGI curators] |