| Primary Identifier | MGI:109446 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 13446 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable calcium-dependent phospholipid binding activity and metal ion binding activity. Involved in calcium-dependent activation of synaptic vesicle fusion and regulation of calcium ion-dependent exocytosis. Acts upstream of or within spontaneous neurotransmitter secretion. Predicted to be located in cell junction; lysosome; and nuclear lumen. Predicted to be active in glutamatergic synapse. Predicted to be extrinsic component of synaptic vesicle membrane. Is expressed in cerebral cortex. Orthologous to human DOC2A (double C2 domain alpha). PHENOTYPE: Homozygous inactivation of this locus affects excitatory synaptic transmission, LTP, and learning/memory. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
