Primary Identifier | MGI:1925638 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 78388 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity; protein kinase binding activity; and protein phosphatase binding activity. Involved in cell population proliferation and protein activation cascade. Predicted to be located in cytoskeleton; cytosol; and perinuclear region of cytoplasm. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasm and nucleus. Is expressed in cranial ganglion; gut; and skeleton. Orthologous to human MVP (major vault protein). PHENOTYPE: Targeted disruption of this gene does not induce hypersensitivity to various cytostatic agents. Homozygotes are viable, healthy and phenotypically normal and exhibit unimpaired dendritic cell maturation and function. [provided by MGI curators] |