Primary Identifier | MGI:2444036 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 100043597 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ATP hydrolysis activity and histone binding activity. Predicted to be involved in chromatin remodeling. Predicted to be located in Golgi apparatus; nuclear body; and perinuclear region of cytoplasm. Predicted to be part of Swr1 complex. Is expressed in cerebral cortex ventricular layer; cortical plate; early conceptus; inner cell mass; and oocyte. Human ortholog(s) of this gene implicated in Floating-Harbor syndrome. Orthologous to human SRCAP (Snf2 related CREBBP activator protein). PHENOTYPE: Mice homozygous for a null allele show impaired blastocyst development at E3.5 and early embryonic lethality. [provided by MGI curators] |