| Primary Identifier | MGI:2446244 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 233904 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables histone H3K4 methyltransferase activity. Involved in several processes, including positive regulation of gene expression; regulation of chromatin organization; and regulation of erythrocyte differentiation. Acts upstream of or within positive regulation of neural precursor cell proliferation; positive regulation of stem cell proliferation; and stem cell population maintenance. Located in euchromatin and nucleus. Is expressed in several structures, including early conceptus; integumental system; liver; nervous system; and oocyte. Used to study schizophrenia. Human ortholog(s) of this gene implicated in early-onset epilepsy 2 and neurodevelopmental disorder with speech impairment and dysmorphic facies. Orthologous to human SETD1A (SET domain containing 1A, histone lysine methyltransferase). PHENOTYPE: Animals homozygous for this allele were dead by E7.5 [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
