| Primary Identifier | MGI:1915023 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 67773 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables enzyme binding activity; histone H4K16 acetyltransferase activity; and promoter-specific chromatin binding activity. Involved in several processes, including positive regulation of skeletal muscle satellite cell differentiation; post-embryonic hemopoiesis; and regulation of gene expression. Located in kinetochore and nuclear matrix. Part of MSL complex and NSL complex. Is active in chromosome; mitochondrion; and nucleus. Is expressed in several structures, including genitourinary system; hemolymphoid system gland; limb; nervous system; and respiratory system. Orthologous to human KAT8 (lysine acetyltransferase 8). PHENOTYPE: Mice homozygous for a null allele die prior to gastrulation. Mice homozygous for a floxed allele deleted in the brain exhibit prenatal lethality, intraventricular hemorrhage, enlarged lateral ventricles, and abnormal brain vasculature. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
