| Primary Identifier | MGI:2384586 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 233912 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including T cell activation; adrenal cortex development; and defense response to virus. Located in membrane. Is expressed in thymus primordium. Human ortholog(s) of this gene implicated in ACTH-independent macronodular adrenal hyperplasia 2. Orthologous to human ARMC5 (armadillo repeat containing 5). PHENOTYPE: Mice homozygous for a knock-out allele exhibit embryonic lethality with defects in mesoderm formation and gastrulation. The few survbiving mice are smaller than normal. Mice heterozygous for the same allele exhibit abnormal adrenocortical morphology and function. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
