| Primary Identifier | MGI:102784 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 21804 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including I-SMAD binding activity; Roundabout binding activity; and nuclear androgen receptor binding activity. Acts upstream of or within several processes, including epithelial cell differentiation; morphogenesis of embryonic epithelium; and negative regulation of fat cell differentiation. Located in focal adhesion. Is expressed in several structures, including bronchus; central nervous system; genitourinary system; heart; and vertebral axis musculature. Orthologous to human TGFB1I1 (transforming growth factor beta 1 induced transcript 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal response to wire injury of femoral arteries and increased VSMC apoptosis in response to wire injury or mechanical stress. Mice homozygous for a different knock-out allele show normal platelet integrin function both in vitro and in vivo. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
