Primary Identifier | MGI:2450915 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 207352 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable phospholipase activity. Acts upstream of or within acrosome assembly and single fertilization. Located in cis-Golgi network; endoplasmic reticulum exit site; and perinuclear endoplasmic reticulum. Orthologous to human SEC23IP (SEC23 interacting protein). PHENOTYPE: Mice homozygous for a null allele exhibit male subfertility associated with impaired in vitro fertilization, abnormal acrosome biogenesis, and round-headed spermatozoa. Female fertility is normal. [provided by MGI curators] |