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Protein Coding Gene : Ate1 arginyltransferase 1
Primary Identifier  MGI:1333870 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  11907
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables arginyl-tRNA--protein transferase activity. Involved in ubiquitin-dependent protein catabolic process. Acts upstream of or within protein arginylation. Located in cytoplasm and nucleus. Is expressed in several structures, including embryo mesenchyme; eye; heart; nervous system; and notochord. Orthologous to human ATE1 (arginyltransferase 1).
PHENOTYPE: Homozygous mutation of this gene results in developmental defects of the heart and embryonic lethality between E13.5 and E15.5. [provided by MGI curators]
  • synonyms:
  • MGI:2141882,
  • Ate1_1,
  • expressed sequence AW547406,
  • arginyltransferase 1,
  • Ate1_3,
  • expressed sequence AI225793,
  • Ate1,
  • Ate1_2,
  • AW547406,
  • MGI:2142257,
  • Ate1_4,
  • AI225793
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