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Protein Coding Gene : Cuzd1 CUB and zona pellucida-like domains 1
Primary Identifier  MGI:1202881 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  16433
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Involved in trypsinogen activation. Located in zymogen granule membrane. Orthologous to human CUZD1 (CUB and zona pellucida like domains 1).
PHENOTYPE: Female mice homozygous for disruption of this gene exhibit impaired mammary gland development during puberty and during and following pregnancy and do not lactate. Homozygous mutant mice show an increased susceptibility to induced pancreatitis. [provided by MGI curators]
  • synonyms:
  • ERG-1,
  • integral membrane-associated protein 1,
  • UTCZP,
  • Cuzd1,
  • CUB and zona pellucida-like domains 1,
  • Itmap1,
  • UO-44
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