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Protein Coding Gene : Bub3 BUB3 mitotic checkpoint protein
Primary Identifier  MGI:1343463 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  12237
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable ubiquitin binding activity. Involved in regulation of chromosome segregation. Located in kinetochore. Is expressed in brain and otolith organ. Orthologous to human BUB3 (BUB3 mitotic checkpoint protein).
PHENOTYPE: Homozygous mutation of this gene results in embryonic lethality by E8.5. [provided by MGI curators]
  • synonyms:
  • AU019800,
  • MGI:2142325,
  • MGI:2146981,
  • MGI:2142137,
  • expressed sequence C78067,
  • expressed sequence AU019800,
  • expressed sequence AW146323,
  • AW146323,
  • Bub3,
  • AU021329,
  • MGI:2142160,
  • AU043350,
  • C78067,
  • BUB3 mitotic checkpoint protein,
  • MGI:2142214,
  • expressed sequence AU043350,
  • expressed sequence AU021329
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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

28 Pathways

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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