Primary Identifier | MGI:1276125 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 22286 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables HMG box domain binding activity; TBP-class protein binding activity; and transcription coactivator activity. Involved in positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including early conceptus; embryo ectoderm; gonad; and limb mesenchyme. Orthologous to human UTF1 (undifferentiated embryonic cell transcription factor 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit growth retardation and background sensitive neo- and postnatal lethality. [provided by MGI curators] |