| Primary Identifier | MGI:1891830 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 56460 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable alpha-catenin binding activity; cadherin binding activity; and enzyme binding activity. Involved in several processes, including desmosome assembly; epithelial structure maintenance; and positive regulation of cell cycle G1/S phase transition. Located in adherens junction; cytoplasm; and desmosome. Is active in cornified envelope. Is expressed in facial prominence ectoderm; mandibular process ectoderm; mandibular process mesenchyme; palatal shelf; and skin. Orthologous to human PKP3 (plakophilin 3). PHENOTYPE: Mice homozygous for a null allele exhibit retarded hair growth, epidermal thickening and abnormal hair follicles that lead to secondary alopecia and acute dermatitis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
