| Primary Identifier | MGI:1344402 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 24058 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in acute-phase response; negative regulation of chemokine production; and negative regulation of interleukin-1-mediated signaling pathway. Predicted to be located in membrane. Predicted to be active in cell surface and plasma membrane. Is expressed in male reproductive system and urinary system. Orthologous to human SIGIRR (single Ig and TIR domain containing). PHENOTYPE: When challenged, homozygous mutant mice show an increased inflammatory response. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
