| Primary Identifier | MGI:1195456 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 107702 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ribonuclease inhibitor activity. Predicted to be involved in cell migration; regulation of Arp2/3 complex-mediated actin nucleation; and regulation of angiogenesis. Predicted to be located in cytosol. Predicted to be part of angiogenin-PRI complex. Predicted to be active in several cellular components, including lamellipodium; nucleoplasm; and plasma membrane. Is expressed in bladder; blood; embryo; pancreas; and yolk sac. Orthologous to human RNH1 (ribonuclease/angiogenin inhibitor 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete embryonic lethality and anemia associated with defects in embryonic erythropoiesis, erythroid differentiation, and GATA1 translation. Heterozygotes exhibit decreased adult erythropoiesis in spleen. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
