Primary Identifier | MGI:1919290 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 72040 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable beta-catenin binding activity; calcium ion binding activity; and cell adhesion molecule binding activity. Predicted to be involved in intermicrovillar adhesion and regulation of microvillus length. Predicted to be located in apical plasma membrane; cell projection membrane; and clathrin-coated pit. Predicted to be active in plasma membrane. Is expressed in liver; lung; metanephros; placenta; and yolk sac. Orthologous to human CDHR5 (cadherin related family member 5). PHENOTYPE: Mice homozygous for a knock-out allele exhibit a slight increase of cell proliferation in the intestinal epithelium but no significant alterations in lifespan or spontaneous tumor incidence. [provided by MGI curators] |