Primary Identifier | MGI:99466 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 20287 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable digestive hormone activity. Involved in several processes, including diet induced thermogenesis; hippocampus development; and regulation of appetite. Acts upstream of or within several processes, including dentate gyrus development; neuronal stem cell population maintenance; and visual learning. Predicted to be active in extracellular space. Is expressed in several structures, including brain; ectoplacental cone; gut; metanephros; and visceral pericardium. Orthologous to human SCT (secretin). PHENOTYPE: Mice homozygous for a null allele display impaired hippocampal synaptic function. Mice homozygous for a different knock-out allele fail to exhibit increased water consumption or vasopressin serum levels in response to ANGII treatment. [provided by MGI curators] |