Primary Identifier | MGI:1274789 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 21351 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity and transaldolase activity. Involved in pentose-phosphate shunt. Located in cytoplasm and nucleus. Is active in cytosol. Is expressed in several structures, including alimentary system; cranium; eye; genitourinary system; and nervous system. Human ortholog(s) of this gene implicated in carbohydrate metabolic disorder. Orthologous to human TALDO1 (transaldolase 1). PHENOTYPE: Homozygous mutation of this gene results in male infertility due to defective sperm motility because of functional and structural defects of mitochondria in the sperm. Heterozygous mice show reduced male fertility. [provided by MGI curators] |