Primary Identifier | MGI:1336884 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 18400 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in xenobiotic detoxification by transmembrane export across the plasma membrane. Predicted to act upstream of or within monoatomic anion transport. Predicted to be located in apical plasma membrane and cytoplasm. Predicted to be active in nuclear envelope. Is expressed in several structures, including liver; metanephros; nervous system; reproductive system; and yolk sac. Human ortholog(s) of this gene implicated in breast cancer; esophagus adenocarcinoma; and lung cancer. Orthologous to human SLC22A18 (solute carrier family 22 member 18). PHENOTYPE: Homozygous null mice show decreased hepatic triglyceride content under refeeding conditions following fasting. [provided by MGI curators] |