|  Help  |  About  |  Contact Us

Protein Coding Gene : Mrgprd MAS-related GPR, member D

Primary Identifier  MGI:3033142 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  211578
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables G protein-coupled peptide receptor activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure. Predicted to be active in plasma membrane. Is expressed in genitourinary system; nervous system; and skin. Used to study dilated cardiomyopathy. Orthologous to human MRGPRD (MAS related GPR family member D).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased sensitivity to cold, heat, and mechanical stimuli. Mice for another null allele exhibit dilated cardiomypathy and cardiac dysfunction. [provided by MGI curators]
  • synonyms:
  • MAS-related GPR, member D,
  • Gm499,
  • Mrgprd,
  • gene model 499, (NCBI),
  • MGI:2685345,
  • LOC211578,
  • MrgD

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

2 Driver For