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Protein Coding Gene : Xab2 XPA binding protein 2
Primary Identifier  MGI:1914689 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  67439
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Acts upstream of or within blastocyst development. Predicted to be located in nucleoplasm. Predicted to be part of Prp19 complex; U2-type catalytic step 2 spliceosome; and post-mRNA release spliceosomal complex. Is expressed in central nervous system; embryo mesenchyme; and retina layer. Orthologous to human XAB2 (XPA binding protein 2).
PHENOTYPE: Homozygous null embryos die by the blastocyst stage (E3.5) and some eight-cell stage embryos do not undergo compaction. [provided by MGI curators]
  • synonyms:
  • Xab2,
  • MGI:2142733,
  • RIKEN cDNA 0610041O14 gene,
  • expressed sequence AV025587,
  • AV025587,
  • 0610041O14Rik,
  • XPA binding protein 2
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