Primary Identifier | MGI:2157942 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 170786 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables D-mannose binding activity and carbohydrate derivative binding activity. Predicted to be involved in immune response. Predicted to act upstream of or within regulation of T cell proliferation. Located in cell surface. Human ortholog(s) of this gene implicated in Coronavirus infectious disease (multiple); aspergillosis; dengue disease (multiple); human immunodeficiency virus infectious disease (multiple); and tuberculosis (multiple). Orthologous to several human genes including CD209 (CD209 molecule). PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal susceptibility to bacterial infection despite altered lymphocyte numbers and increased inflammatory response.. [provided by MGI curators] |