| Primary Identifier | MGI:1919517 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 72267 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable volume-sensitive anion channel activity. Involved in cyclic-GMP-AMP transmembrane import across plasma membrane. Predicted to be located in endoplasmic reticulum membrane and lysosomal membrane. Predicted to be part of monoatomic ion channel complex. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human LRRC8E (leucine rich repeat containing 8 VRAC subunit E). PHENOTYPE: Mice homozygous for a null allele exhibit impaired response to HSV-1 infection. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
