| Primary Identifier | MGI:1100851 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 15568 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables lncRNA binding activity and mRNA 3'-UTR AU-rich region binding activity. Involved in post-transcriptional regulation of gene expression; protein import into nucleus; and regulation of stem cell population maintenance. Acts upstream of or within positive regulation of translation. Located in several cellular components, including cytoplasmic stress granule; endoplasmic reticulum; and sarcoplasm. Part of ribonucleoprotein complex. Is active in cytoplasmic vesicle; glutamatergic synapse; and postsynapse. Is expressed in several structures, including alimentary system; central nervous system; connective tissue; early conceptus; and genitourinary system. Orthologous to human ELAVL1 (ELAV like RNA binding protein 1). PHENOTYPE: Homozygous inactivation of this gene leads to embryonic growth retardation and midgestational lethality due to placental failure resulting from extraembryonic trophoblast defects. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
