Primary Identifier | MGI:1099448 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 20300 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables chemokine activity. Acts upstream of or within chemotaxis; leukocyte migration; and lymphoid lineage cell migration. Predicted to be active in extracellular space. Is expressed in 3rd branchial pouch; central nervous system; hemolymphoid system; retina; and thymus/parathyroid primordium. Orthologous to human CCL25 (C-C motif chemokine ligand 25). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired accumulation of antigen-specific CD8+ T lymphocytes within both lamina propria and epithelium of the small intestine. [provided by MGI curators] |