| Primary Identifier | MGI:2442985 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 234023 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables nuclear receptor coactivator activity and pre-mRNA binding activity. Involved in regulation of alternative mRNA splicing, via spliceosome. Located in nuclear speck. Is expressed in several structures, including brain; genitourinary system; gut; immune system; and leg muscle. Orthologous to human ARGLU1 (arginine and glutamate rich 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit embryonic growth retardation, increased brain apoptosis, and complete embryonic lethality during organogenesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
