| Primary Identifier | MGI:1349481 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 26356 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable methylated histone binding activity. Acts upstream of or within positive regulation of DNA-templated transcription; protein import into nucleus; and regulation of programmed cell death. Located in nucleus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; hemolymphoid system gland; and liver. Human ortholog(s) of this gene implicated in head and neck squamous cell carcinoma and squamous cell carcinoma. Orthologous to human ING1 (inhibitor of growth family member 1). PHENOTYPE: Homozygous null mice display a slight decrease in body weight, moderately impaired maternal nurturing, increased sensitivity to gamma-irradiation, and increased incidence of B-cell derived lymphomas. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
