| Primary Identifier | MGI:2443003 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 234069 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Predicted to enable RNA binding activity and double-stranded DNA binding activity. Involved in several processes, including negative regulation of lymphoid progenitor cell differentiation; positive regulation of B cell differentiation; and spleen development. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of nuclear pore nuclear basket and transcription export complex 2. Is expressed in lung; nervous system; retina layer; and skeletal muscle. Orthologous to human PCID2 (PCI domain containing 2). PHENOTYPE: Homozygotes for a targeted null mutation implant, but die prior to embryonic day 7.5. Heterozygotes also exhibit excess embryonic loss. [provided by MGI curators] |