Primary Identifier | MGI:2443181 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 244310 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable molecular adaptor activity and protein domain specific binding activity. Involved in regulation of postsynaptic neurotransmitter receptor activity. Is active in glutamatergic synapse and postsynaptic density, intracellular component. Is expressed in cranium and nervous system. Orthologous to human DLGAP2 (DLG associated protein 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit novelty-induced hyperactivity, increased aggression, impaired reverse learning, decreased dendritic spine density, synaptopathies, reduced mESPC amplitude and enhanced paired-pulse ratio. [provided by MGI curators] |