| Primary Identifier | MGI:2142716 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 102247 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables glycerol-3-phosphate O-acyltransferase activity. Involved in lactation and triglyceride biosynthetic process. Acts upstream of or within several processes, including acylglycerol metabolic process; glandular epithelial cell maturation; and mammary gland development. Located in endoplasmic reticulum. Is expressed in several structures, including adipose tissue; genitourinary system; liver; mammary gland; and spleen. Orthologous to human GPAT4 (glycerol-3-phosphate acyltransferase 4). PHENOTYPE: Nursing mothers homozygous for a gene trap allele display underdeveloped mammary glands that are depleted in intracellular fat droplets and lack the ability to produce diacylglycerol- and triacylglycerol-rich milk; pups nursed by mutant mothers die neonatally unless transferred to foster mothers. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
