Primary Identifier | MGI:1916318 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 69068 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable Notch binding activity. Acts upstream of or within regulation of hemopoiesis. Located in cytoplasm and nucleus. Is expressed in lower jaw molar; nasal epithelium; olfactory epithelium; and upper jaw molar. Orthologous to human TCIM (transcriptional and immune response regulator). PHENOTYPE: Mice homozygous for a knock-out allele exhibit myeloid and lymphoid hyperplasia, an increased number of small-sized red blood cells, increased hematopoietic stem cell number, and enhanced hematopoietic activity. [provided by MGI curators] |