Primary Identifier | MGI:1344416 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 23808 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable beta-catenin binding activity and transcription cis-regulatory region binding activity. Predicted to contribute to histone H3K4 methyltransferase activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in euchromatin. Part of MLL1 complex. Is expressed in several structures, including alimentary system; brain; branchial arch; genitourinary system; and heart. Orthologous to human ASH2L (ASH2 like, histone lysine methyltransferase complex subunit). PHENOTYPE: Mice homozygous for a gene trapped allele die before E8.5-E11.5. [provided by MGI curators] |