Primary Identifier | MGI:2389364 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 210801 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable netrin receptor activity. Acts upstream of or within axon guidance; pyramidal neuron differentiation; and regulation of neuron migration. Located in cell surface. Is expressed in several structures, including brain; female reproductive system; jaw; limb; and sensory organ. Orthologous to human UNC5D (unc-5 netrin receptor D). PHENOTYPE: Mice exhibit impaired induced growth cone collapse response and accelerated radial migration of cortical neurons. [provided by MGI curators] |