Primary Identifier | MGI:1321161 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 19053 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein serine/threonine phosphatase activity and transmembrane transporter binding activity. Acts upstream of or within several processes, including apoptotic mitochondrial changes; proteasome-mediated ubiquitin-dependent protein catabolic process; and response to hydrogen peroxide. Located in cytoplasm. Part of protein phosphatase type 2A complex. Is expressed in several structures, including cardiovascular system; central nervous system; eye; genitourinary system; and gut. Orthologous to human PPP2CB (protein phosphatase 2 catalytic subunit beta). PHENOTYPE: Mice homozygous for a knock-out allele are viable and fertile. [provided by MGI curators] |