| Primary Identifier | MGI:1343154 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 22428 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables dynein complex binding activity. Acts upstream of or within mitotic spindle organization. Part of dynactin complex. Is expressed in embryo; extraembryonic component; oocyte; primitive endoderm; and yolk sac. Orthologous to human DCTN6 (dynactin subunit 6). PHENOTYPE: Mice homozygous for a knock-out allele show complete lethality prior to organogenesis. Cultured blastocysts fail to hatch from the zona pellucida, show apparent cell death, and form atypical outgrowth colonies with no trophectoderm, primitive endoderm or epiblast cells. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
