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Protein Coding Gene : Eri1 exoribonuclease 1
Primary Identifier  MGI:1914526 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  67276
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables histone pre-mRNA stem-loop binding activity; rRNA binding activity; and ribosome binding activity. Involved in rRNA 3'-end processing. Located in cytoplasm and nucleolus. Part of histone pre-mRNA 3'end processing complex. Is expressed in early conceptus; eye; inner cell mass; limb; and oocyte. Orthologous to human ERI1 (exoribonuclease 1).
PHENOTYPE: Mice homozygous for a null allele exhibit postnatal lethality, decreased body size beginning at E15.5, and decreased proliferation of mouse embryonic fibroblasts. [provided by MGI curators]
  • synonyms:
  • exoribonuclease 1,
  • 3110010F15Rik,
  • three prime histone mRNA exonuclease 1,
  • Thex1,
  • Eri1,
  • RIKEN cDNA 3110010F15 gene
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