| Primary Identifier | MGI:102795 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 234199 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity. Involved in negative regulation of T cell activation; regulation of immune response; and response to stilbenoid. Acts upstream of or within adipose tissue development; cholesterol metabolic process; and regulation of glucose metabolic process. Located in extracellular region. Orthologous to human FGL1 (fibrinogen like 1). PHENOTYPE: Mice homozygous for one null allele exhibit increased body weight, white fat and gluconeogenesis, decreased circulating cholesterol, free fatty acid level and respiratory quotient, hyperglycemia, and impaired glucose tolerance. Mice homozygous for a second null allele display normal appearance with age-related onset of dermatitis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
