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Protein Coding Gene : Pcm1 pericentriolar material 1

Primary Identifier  MGI:1277958 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  18536
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable molecular adaptor activity. Involved in several processes, including interkinetic nuclear migration; microtubule anchoring; and protein localization to centrosome. Acts upstream of or within several processes, including microtubule anchoring at centrosome; neuronal stem cell population maintenance; and social behavior. Located in apical part of cell; cytoplasm; and microtubule organizing center. Colocalizes with centrosome. Is expressed in brain; cardiac muscle tissue; and cerebral cortex ventricular layer. Orthologous to human PCM1 (pericentriolar material 1).
PHENOTYPE: Haploinsufficient mice show a reduced brain size, behavioral impairment to social stimulus and reduced rearing in the open field test. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 2600002H09 gene,
  • RIKEN cDNA C030044G17 gene,
  • 9430077F19Rik,
  • 2600002H09Rik,
  • Pcm1,
  • RIKEN cDNA 9430077F19 gene,
  • pericentriolar material 1,
  • MGI:1919589,
  • MGI:1924673,
  • C030044G17Rik,
  • MGI:1924736

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Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

16 Pathways

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Expression

Gene --> Expression annotations

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Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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