| Primary Identifier | MGI:102967 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 17773 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable hormone binding activity; melatonin receptor activity; and organic cyclic compound binding activity. Predicted to be involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway and negative regulation of insulin secretion. Predicted to act upstream of or within circadian rhythm. Predicted to be located in neuronal cell body. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including adrenal gland; alimentary system; brain; liver and biliary system; and reproductive system. Orthologous to human MTNR1A (melatonin receptor 1A). PHENOTYPE: Mice homozygous for disruptions in this gene are essentially normal, with normal circadian functions. In vitro studies report the absence of inhibitory effects of melatonin on suprachiasma neuronal firing. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
