| Primary Identifier | MGI:99481 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 109821 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity and serine-type aminopeptidase activity. Acts upstream of or within regulation of blood coagulation. Predicted to be located in extracellular space. Is expressed in liver; liver left lobe; and liver right lobe. Used to study factor XI deficiency. Human ortholog(s) of this gene implicated in factor XI deficiency and thrombosis. Orthologous to human F11 (coagulation factor XI). PHENOTYPE: Mice homozygous for a knock-out allele show a tendency for slightly prolonged tail transection bleeding times and are protected from vessel-occluding fibrin formation after transient ischemic brain injury. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
