| Primary Identifier | MGI:102797 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 14081 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein serine/threonine kinase activator activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within adiponectin-activated signaling pathway. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; metanephros; respiratory system; and sensory organ. Used to study cardiomyopathy. Orthologous to human ACSL1 (acyl-CoA synthetase long chain family member 1). PHENOTYPE: Liver acyl-CoA levels are reduced when this gene is conditionally knocked out in the liver. Impaired adaptive thermogenesis when this gene is conditionally knocked out in adipose tissue. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
