| Primary Identifier | MGI:3603756 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 408022 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA primase activity. Involved in mitochondrial DNA repair and mitochondrial DNA replication. Predicted to be located in replication fork. Predicted to be part of DNA-directed RNA polymerase complex. Predicted to be active in mitochondrial matrix and nucleus. Is expressed in several structures, including aorta; brain; endocrine gland; genitourinary system; and trachea. Human ortholog(s) of this gene implicated in myopia. Orthologous to human PRIMPOL (primase and DNA directed polymerase). PHENOTYPE: Homozygous null mutants are viable and fertile. Mice homozygous for another knock-out allele exhibit selective increase in C to G transversions in B cells. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
