Primary Identifier | MGI:2384588 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 234258 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA binding activity and catalytic activity, acting on DNA. Involved in base-excision repair. Located in nucleus. Is expressed in several structures, including brain; genitourinary system; liver; retina nuclear layer; and spleen. Orthologous to human NEIL3 (nei like DNA glycosylase 3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased neurogenesis following hypoxia-ischemia. [provided by MGI curators] |