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Protein Coding Gene : Ddx60 DExD/H box helicase 60
Primary Identifier  MGI:2384570 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  234311
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables RNA binding activity. Acts upstream of or within defense response to virus. Located in cytoplasm. Is expressed in lens. Orthologous to human DDX60 (DExD/H-box helicase 60).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal immunity to several viruses (IAV, EMCV, SINV) but increased susceptibility to VSV infection. [provided by MGI curators]
  • synonyms:
  • cDNA sequence BC013672,
  • BC013672,
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 60,
  • DExD/H box helicase 60,
  • Ddx60,
  • MGC:19297
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1 Involved In Mutations

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