Primary Identifier | MGI:1931321 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 80720 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables sequence-specific DNA binding activity. Predicted to be involved in several processes, including embryonic organ development; eye development; and nervous system development. Located in XY body. Is expressed in several structures, including central nervous system; eye; gonad; heart; and urinary system. Orthologous to human PBX4 (PBX homeobox 4). PHENOTYPE: Mice homozygous for a knock-out allele exhibit no apparent abnormality in spermatogenesis but show postnatal growth retardation, inactivity, shorter hindlimbs and hindlimb disability, anemia, lower numbers of reticulocytes and lymphocytes, a decreased erythropoietin level, and premature death. [provided by MGI curators] |