Primary Identifier | MGI:2679531 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 330790 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) A structural constituent of synapse-associated extracellular matrix. Involved in GABAergic synaptic transmission and inhibitory synapse assembly. Located in perineuronal net. Is expressed in brain and liver. Orthologous to human HAPLN4 (hyaluronan and proteoglycan link protein 4). PHENOTYPE: Mice homozygous for a knock-out allele exhibit attenuated perineuronal nets and synapses. [provided by MGI curators] |