| Primary Identifier | MGI:107995 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 19704 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including ATP hydrolysis activity; helicase activity; and nucleic acid binding activity. Acts upstream of or within positive regulation of mRNA cis splicing, via spliceosome. Predicted to be located in chromosome; cytosol; and nucleoplasm. Predicted to be part of exon-exon junction complex and supraspliceosomal complex. Predicted to be active in cytoplasm. Is expressed in cerebral cortex ventricular layer; cumulus oophorus; embryo; and oocyte. Orthologous to human UPF1 (UPF1 RNA helicase and ATPase). PHENOTYPE: Mice homozygous for a targeted null mutation are viable in the pre-implantation period but resorb in the early post-implantation period. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
