Primary Identifier | MGI:1354692 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 50783 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable PH domain binding activity and U6 snRNA binding activity. Predicted to be involved in P-body assembly and spliceosomal snRNP assembly. Predicted to be located in cytosol; membrane; and nucleoplasm. Predicted to be part of Lsm2-8 complex; U2-type precatalytic spliceosome; and spliceosomal snRNP complex. Predicted to be active in P-body. Is expressed in several structures, including branchial arch; central nervous system; jaw; limb; and sensory organ. Orthologous to human LSM4 (LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated). PHENOTYPE: Embryos homozygous for a gene trap mutation in this gene die in the peri-implantation stage. [provided by MGI curators] |