Primary Identifier | MGI:99556 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 110385 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable 3',5'-cyclic-AMP phosphodiesterase activity and 3',5'-cyclic-GMP phosphodiesterase activity. Predicted to be involved in cAMP-mediated signaling and negative regulation of insulin secretion involved in cellular response to glucose stimulus. Located in cilium. Is expressed in brain; gonad; metanephros; and submandibular gland. Orthologous to human PDE4C (phosphodiesterase 4C). PHENOTYPE: Mice homozygous for a null allele exhibit normal righting response following treatment with RS25344. [provided by MGI curators] |